Literature
PubMed
PubMed® comprises more than 37 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites.
Featured Bookshelf titles
Drug Therapy for Early Rheumatoid Arthritis
A Systematic Review Update
Donahue KE, Gartlehner G, Schulman ER, et al.
Drugs and Lactation Database (LactMed®)
Browse the Bookshelf
Literature databases
Bookshelf
Books and reports
MeSH
Ontology used for PubMed indexing
NLM Catalog
Books, journals and more in the NLM Collections
PubMed
Scientific and medical abstracts/citations
PubMed Central
Full-text journal articles
Data
Genes
Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution
Gene
Collected information about gene loci
GEO DataSets
Functional genomics studies
GEO Profiles
Gene expression and molecular abundance profiles
PopSet
Sequence sets from phylogenetic and population studies
Proteins
Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites
Conserved Domains
Conserved protein domains
Identical Protein Groups
Protein sequences grouped by identity
Protein
Protein sequences
Protein Family Models
Models representing hom*ologous proteins with a common function
Structure
Experimentally-determined biomolecular structures
BLAST
A tool to find regions of similarity between biological sequences
blastn
Search nucleotide sequence databases
blastp
Search protein sequence databases
blastx
Search protein databases using a translated nucleotide query
tblastn
Search translated nucleotide databases using a protein query
Primer-BLAST
Find primers specific to your PCR template
Genomes
Genome sequence assemblies, large-scale functional genomics data, and source biological samples
Assembly
Genome assembly information
BioCollections
Museum, herbaria, and other biorepository collections
BioProject
Biological projects providing data to NCBI
BioSample
Descriptions of biological source materials
Genome
Genome sequencing projects by organism
Nucleotide
DNA and RNA sequences
SRA
High-throughput sequence reads
Taxonomy
Taxonomic classification and nomenclature
Clinical
Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments
ClinicalTrials.gov
Privately and publicly funded clinical studies conducted around the world
ClinVar
Human variations of clinical significance
dbGaP
Genotype/phenotype interaction studies
dbSNP
Short genetic variations
dbVar
Genome structural variation studies
GTR
Genetic testing registry
MedGen
Medical genetics literature and links
OMIM
Online mendelian inheritance in man
PubChem
Repository of chemical information, molecular pathways, and tools for bioactivity screening
BioAssays
Bioactivity screening studies
Compounds
Chemical information with structures, information and links
Pathways
Molecular pathways with links to genes, proteins and chemicals
Substances
Deposited substance and chemical information
News
Research news
NIH Research Matters JUNE 25, 2024
Providing lasting protection from peanut allergy
Children who regularly ate peanut-containing foods early in life had a greatly reduced risk of developing peanut allergy into adolescence.
NIH Research Matters JUNE 25, 2024
Quick test could help reduce dementia care disparities
A five-minute, culturally neutral test for cognitive problems improved dementia detection and management in older adults.
The Scientist JUNE 25, 2024
Moo-ve Aside Mice: Exploring Cow Models in Research
Humans have more in common with cows than mice when it boils down to bone marrow stem cells.
Recent blog posts
NIH Director's Blog JUNE 27, 2024
Molecular Portrait of Key Driver of Pancreatic Cancer Offers Hope for Continued Treatment Advances
Cancer arises when changes in genes that normally control cell division lead to unchecked growth at the expense of healthy tissues. One of the most common genetic alterations across human cancers—occurring in 95% of pancreatic cancers but also many non-small cell lung cancers, colorectal cancers, and others—is in a gene known as KRAS. While promising new treatments targeting KRAS to shrink cancerous tumors have recently gained approval, less than 40% of pancreatic cancers respond to treatment with KRAS inhibitors for reasons that aren’t well understood.There’s much more to learn about how KRAS spurs cancer growth—and how KRAS-mutant cancers resist treatment with existing KRAS inhibitors. To address this need, researchers behind two studies in Science have established the most comprehensive molecular portrait yet of the workings of KRAS and how its many downstream impacts may influence outcomes for people with pancreatic cancer. The findings could lead to new treatment approaches, including ways to potentially guide treatment for individuals with pancreatic cancer, the third leading cause of cancer-related death in the U.S.
NLM Musings JUNE 26, 2024
The Big Three-O: LOINC Celebrates Three Decades of Standardizing Health Data Terminology
The Logical Observation Identifiers Names and Codes (LOINC) turns 30! Dr. Clem McDonald, creator of LOINC and NLM Senior Investigator, reflects on its history and achievements and the ways it revolutionized how clinical and laboratory data are documented and shared across healthcare systems.
NCBI Insights JUNE 25, 2024
A Modern ClinicalTrials.gov Website
Classic website no longer available effective June 25, 2024 We appreciate all the feedback received since the launch of the modernized ClinicalTrials.gov website in June 2023, and we’ve incorporated many of your suggestions. As announced last month, the classic website has remained available to help you transition to the modernized website. Effective today, the classic … Continue reading A Modern ClinicalTrials.gov Website →
